이윤성 교수
- 영문이름 -
- Lee Yoonsung
- 교실 -
- 연구전담 전임교원
- 전공 -
- 분자유전학, 발생생물학
- 연락처 -
- 02-440-6290
- 연구실 -
- 강동경희대병원 신관(서희빌딩) 434호 (질환모델중개연구센터 Ⅰ)
- E-mail -
- ylee3699@khu.ac.kr
- 제브라피쉬 질환 모델 및 신약개발 플랫폼 개발
- 조혈 발생 및 유전체안정성에 대한 in vivo 기전 연구
- 조혈 발생 및 유전체안정성에 대한 in vivo 기전 연구
- 서울대학교 이과대학 해양학과 학사(1993-2000)
- 서울대학교 이과대학 생명과학부 학사(2000-2002)
- 밴더빌트대학교 의과대학 약리학과 연구원(2002)
- 듀크대학교 의과대학 세포생물학과 박사(2003-2009)
- UCSD 의과대학 세포분자의학과 박사 후 연구원(2009-2015)
- 기초과학연구원 유전체항상성연구단, 섹션헤드(2015-2021)
- 울산과학기술원 생명과학부 겸임교수(2018-2021)
- 경희대학교 의과대학 의학과 부교수(2021-)
- 서울대학교 이과대학 생명과학부 학사(2000-2002)
- 밴더빌트대학교 의과대학 약리학과 연구원(2002)
- 듀크대학교 의과대학 세포생물학과 박사(2003-2009)
- UCSD 의과대학 세포분자의학과 박사 후 연구원(2009-2015)
- 기초과학연구원 유전체항상성연구단, 섹션헤드(2015-2021)
- 울산과학기술원 생명과학부 겸임교수(2018-2021)
- 경희대학교 의과대학 의학과 부교수(2021-)
- 생화학분자생물학회
- 한국분자세포생물학회
- 국제제브라피쉬질병모델학회
- 국제발생생물학회
- 국제실험혈액학회
- 한국분자세포생물학회
- 국제제브라피쉬질병모델학회
- 국제발생생물학회
- 국제실험혈액학회
- Shin, U., Nakhro, K., Oh, C.K., Carrington, B., Song, H., Varshney, G.K., Kim, Y., Song, H., Jeon, S., Robbins, G., Kim, S., Yoon, S., Choi, Y. J., Kim, Y. J., Burgess, S., Kang, S., Sood, R., Lee,Y.*, Myung, K. (2021) Large-scale generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes. DNA Repair (Amst) 107, 103173. (*Co-correspondence).
- Espanola, S.G., Song,1 H., Ryu, E., Saxena, A., Kim, E., Manegold, J.E., Nasamran, C.A., Sahoo, D., Oh, C.K., Bickers, C., Shin, U., Grainger, S., Park, Y.H., Pandolfo, L., Kang, M., Kang, S., Myung, K., Cooper, K.L., Yelon, D., Traver, D., Lee,Y. (2020). Haematopoietic Stem Cell-Dependent Notch Transcription is Mediated by p53 through the Histone Chaperone Supt16h. Nat Cell Biol 22, 1411-1422.
- Shashi, V., Geist, J., Lee, Y. Yoo, Y., Shin, U., Schoch, K., Sullivan, J., J, Stong, N., Smith, E., Jasien, J., Kranz, P; Undiagnosed Diseases Network, Lee,Y., Shin, Y.B., Wright, N.T., Choi, M., Kontrogianni-Konstantopoulos, A. (2019). Heterozygous Variants in MYBPC1 are associated with an Expanded Neuromuscular Phenotype beyond Arthrogryposis. Hum Mutat 40, 1115-1126.
- Han, S.H.*, Kim, S.H.*, Kim, H.J.*, Lee,Y.*, Choi, S.Y., Park, G., Kim, D.H., Lee, A., Kim, J., Choi, J.M., Kim, Y., Myung, K., Kim, H., Kim, D.W. (2017). Cobll1 is linked to drug resistance and blastic transformation in chronic myeloid leukemia. Leukemia 31, 1532-1539. (*These authors contributed equally).
- Lee, Y., Manegold, J.E., Kim, A.D., Pouget, C., Stachura, D.L., Clements, W.K., Traver, D. (2014). FGF signaling specifies hematopoietic stem cells through its regulation of somitic Notch signaling. Nat Commun 5, 5583.
- Pouget, C., Peterkin, T., Simoes, F., Lee,Y.,Traver,D.,Patient,R.(2014). FGF restricts BMP signaling and thereby the hematopoietic stem cell program in the dorsal aorta. Nat Commun 5, 5588.
- Shin, D., Lee,Y.,Poss,K.D.,Stainier,D.Y.R.(2011). Restriction of hepatic competence by Fgf signaling. Development 138, 1339-1348.
- Gonzalez-Quevedo, R., Lee,Y.,Poss,K.D.,Wilkinson,D.G.(2010). Neuronal regulation of the spatial patterning of neurogenesis. Dev Cell 18, 136-147.
- Lee, Y., Nachtrab, G., Klinsawat, P.W., Hami, D., Poss, K.D. (2010). Ras controls melanocyte expansion during zebrafish fin stripe regeneration. Dis Model Mech 3, 496-503.
- Lee, Y., Hami, D., De Val, S., Kagermeier-Schenk, B., Wills, A.A., Black, B.L., Weidinger, G., and Poss, K.D. (2009). Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins. Dev Biol 331, 270-280.
- Marques, S.R., Lee,Y., Poss, K.D., and Yelon, D. (2008). Reiterative roles for Fgf signaling in the establishment of size and proportion of the zebrafish heart. Dev Biol 321, 397-406.
- Lee, Y., Grill, S., Sanchez, A., Murphy-Ryan, M., and Poss, K.D. (2005). Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration. Development 132, 5173-5183.
- Espanola, S.G., Song,1 H., Ryu, E., Saxena, A., Kim, E., Manegold, J.E., Nasamran, C.A., Sahoo, D., Oh, C.K., Bickers, C., Shin, U., Grainger, S., Park, Y.H., Pandolfo, L., Kang, M., Kang, S., Myung, K., Cooper, K.L., Yelon, D., Traver, D., Lee,Y. (2020). Haematopoietic Stem Cell-Dependent Notch Transcription is Mediated by p53 through the Histone Chaperone Supt16h. Nat Cell Biol 22, 1411-1422.
- Shashi, V., Geist, J., Lee, Y. Yoo, Y., Shin, U., Schoch, K., Sullivan, J., J, Stong, N., Smith, E., Jasien, J., Kranz, P; Undiagnosed Diseases Network, Lee,Y., Shin, Y.B., Wright, N.T., Choi, M., Kontrogianni-Konstantopoulos, A. (2019). Heterozygous Variants in MYBPC1 are associated with an Expanded Neuromuscular Phenotype beyond Arthrogryposis. Hum Mutat 40, 1115-1126.
- Han, S.H.*, Kim, S.H.*, Kim, H.J.*, Lee,Y.*, Choi, S.Y., Park, G., Kim, D.H., Lee, A., Kim, J., Choi, J.M., Kim, Y., Myung, K., Kim, H., Kim, D.W. (2017). Cobll1 is linked to drug resistance and blastic transformation in chronic myeloid leukemia. Leukemia 31, 1532-1539. (*These authors contributed equally).
- Lee, Y., Manegold, J.E., Kim, A.D., Pouget, C., Stachura, D.L., Clements, W.K., Traver, D. (2014). FGF signaling specifies hematopoietic stem cells through its regulation of somitic Notch signaling. Nat Commun 5, 5583.
- Pouget, C., Peterkin, T., Simoes, F., Lee,Y.,Traver,D.,Patient,R.(2014). FGF restricts BMP signaling and thereby the hematopoietic stem cell program in the dorsal aorta. Nat Commun 5, 5588.
- Shin, D., Lee,Y.,Poss,K.D.,Stainier,D.Y.R.(2011). Restriction of hepatic competence by Fgf signaling. Development 138, 1339-1348.
- Gonzalez-Quevedo, R., Lee,Y.,Poss,K.D.,Wilkinson,D.G.(2010). Neuronal regulation of the spatial patterning of neurogenesis. Dev Cell 18, 136-147.
- Lee, Y., Nachtrab, G., Klinsawat, P.W., Hami, D., Poss, K.D. (2010). Ras controls melanocyte expansion during zebrafish fin stripe regeneration. Dis Model Mech 3, 496-503.
- Lee, Y., Hami, D., De Val, S., Kagermeier-Schenk, B., Wills, A.A., Black, B.L., Weidinger, G., and Poss, K.D. (2009). Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins. Dev Biol 331, 270-280.
- Marques, S.R., Lee,Y., Poss, K.D., and Yelon, D. (2008). Reiterative roles for Fgf signaling in the establishment of size and proportion of the zebrafish heart. Dev Biol 321, 397-406.
- Lee, Y., Grill, S., Sanchez, A., Murphy-Ryan, M., and Poss, K.D. (2005). Fgf signaling instructs position-dependent growth rate during zebrafish fin regeneration. Development 132, 5173-5183.