이화진 교수
- 영문이름 -
- Lee Hwa Jin
- 교실 -
- 생화학&분자생물학교실
- 전공 -
- 연락처 -
- --
- 연구실 -
- E-mail -
- hwajin2k@khu.ac.kr
1. Cancer genomics
- Whole-genome sequencing based somatic mutation analysis
- Somatic mutation density (burden) analysis
- Mutation signature analysis
2. Integration of multi-omics / Machine learning approaches
- Profiling non-random distribution of somatic mutation density and dissecting the relationship with chromatin mark data (ChIP-seq, ATAC-seq, single cell data, etc.)
- Prediction of tissue/cell of origin of multiple types of cancer
3. Single cell –omics data analysis
- Single cell RNA-seq, single cell ATAC-seq on various subjects
- Whole-genome sequencing based somatic mutation analysis
- Somatic mutation density (burden) analysis
- Mutation signature analysis
2. Integration of multi-omics / Machine learning approaches
- Profiling non-random distribution of somatic mutation density and dissecting the relationship with chromatin mark data (ChIP-seq, ATAC-seq, single cell data, etc.)
- Prediction of tissue/cell of origin of multiple types of cancer
3. Single cell –omics data analysis
- Single cell RNA-seq, single cell ATAC-seq on various subjects
1. B.S, Cornell University, 2007
2. Ph.D, Cellular and Molecular Medicine, Johns Hopkins School of Medicine, 2014
3. Research scientist, Celltrion, inc., 2018
4. Adjuct PI, Seoul National University Dental Research Institute, 2023
5. Co-founder, UPPThera, inc.
6. Assistant Professor, Kyung Hee University School of Medicine
2. Ph.D, Cellular and Molecular Medicine, Johns Hopkins School of Medicine, 2014
3. Research scientist, Celltrion, inc., 2018
4. Adjuct PI, Seoul National University Dental Research Institute, 2023
5. Co-founder, UPPThera, inc.
6. Assistant Professor, Kyung Hee University School of Medicine
1. 생화학 분자생물학회 (KSBMB)
2. Pan Cancer Analysis of Whole Genomes (PCAWG)
3. International Cancer Genome Consortium (ICGC)
4. The NIH Roadmap Epigenomics Mapping Consortium
2. Pan Cancer Analysis of Whole Genomes (PCAWG)
3. International Cancer Genome Consortium (ICGC)
4. The NIH Roadmap Epigenomics Mapping Consortium
- Cellular direct conversion by cell penetrable OCT4-30Kc19 protein and BMP4 growth factor
[Biomaterials Research, 2022]
- Subcellular progression of mesenchymal transition identified by two discrete synchronous cell lines derived from the same glioblastoma
[Celluar and Molecular Life Sciences, 2022]
- Hybrid Stomach-Intestinal Chromatin States Underlie Human Barrett's Metaplasia
[Gastroenterology, 2021]
- An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping
[Cell, 2020]
- Ectopic transient overexpression of OCT-4 facilitates BMP4-induced osteogenic transdifferentiation of human umbilical vein endothelial cells
[Journal of Tissue Engineering, 2020]
- Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer
[Heliyon, 2020]
[Biomaterials Research, 2022]
- Subcellular progression of mesenchymal transition identified by two discrete synchronous cell lines derived from the same glioblastoma
[Celluar and Molecular Life Sciences, 2022]
- Hybrid Stomach-Intestinal Chromatin States Underlie Human Barrett's Metaplasia
[Gastroenterology, 2021]
- An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping
[Cell, 2020]
- Ectopic transient overexpression of OCT-4 facilitates BMP4-induced osteogenic transdifferentiation of human umbilical vein endothelial cells
[Journal of Tissue Engineering, 2020]
- Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer
[Heliyon, 2020]