교수소개

처음 메뉴 임상교실

기초교실

기초교실

정주원 교수

영문이름 -
Joo-Won Jeong
교실 -
해부학&신경생물학교실
전공 -
분자생물학
연락처 -
02-961-9103
연구실 -
의학관 B123호
E-mail -
jjeong@khu.ac.kr
홈페이지 -
https://microvascreslab.wixsite.com/mysite
Regulation of blood vessel system in human diseases
- 2017~ 경희대학교 의과대학 교수
- 2012-2016 경희대학교 의과대학 부교수
- 2008-2011 경희대학교 의과대학 조교수
- 2006-2007 경희대학교 의과대학 전임강사
- 2004~2006 Harvard Medical School 박사후연구원
- 2003-2004 서울대학교 종합약학연구소 선임 연구원




- Society for Neuroscience (SFN)
- Harvard Center for Neurodegeneration & Repair (HCNR)
- 대한해부학회
- 한국분자,세포생물학회
- 한국생화학, 분자생물학회
- 혈관학회
- 여성생명과학기술포럼
55: Choi JS, Bae WY, Nam S, Jeong JW*. New Targets for Parkinson's Disease: Adhesion G Protein-Coupled Receptor B1 is Downregulated by AMP-Activated Protein Kinase Activation. OMICS. 2018 Jul;22(7):493-501.

54: Bae WY, Choi JS, Jeong JW*. The Neuroprotective Effects of Cinnamic Aldehyde in an MPTP Mouse Model of Parkinson's Disease. Int J Mol Sci. 2018 Feb 12;19(2). pii: E551.

53: Kim W, Pyo J, Noh BJ, Jeong JW, Lee J, Kim JE. CCAR2 negatively regulates IL-8 production in cervical cancer cells. Oncotarget. 2017 Dec 13;9(1):1143-1155.

52: Choi JS, Kim J, Hong YJ, Bae WY, Choi EH, Jeong JW*, Park HK. Evaluation of non-thermal plasma-induced anticancer effects on human colon cancer cells. Biomed Opt Express. 2017 Apr 26;8(5):2649-2659.

51: Park HJ, Kim MK, Choi KS, Jeong JW, Bae SK, Kim HJ, Bae MK. Neuromedin B receptor antagonism inhibits migration, invasion, and epithelial-mesenchymal transition of breast cancer cells. Int J Oncol. 2016 Sep;49(3):934-42.

50: Bae WY, Choi JS, Kim JE, Park C, Jeong JW*. Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development. Oncotarget. 2016 Jul 26;7(30):47232-47241.

49: Lee SD, Kim W, Jeong JW, Park JW, Kim JE. AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia. Cancer Lett. 2016 Apr 1;373(1):138-145.

48: Kang HM, Sohn I, Jung J, Jeong JW, Park C. Age-related changes in pial arterial structure and blood flow in mice. Neurobiol Aging. 2016 Jan;37:161-170.

47: Kang HM, Sohn I, Jung J, Jeong JW, Park C. Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis. Biochem Biophys Res Commun. 2015 Oct 2;465(4):758-63.

46: Bae WY, Choi JS, Kim JE, Jeong JW*. Cinnamic aldehyde suppresses hypoxia-induced angiogenesis via inhibition of hypoxia-inducible factor-1α expression during tumor progression. Biochem Pharmacol. 2015 Nov 1;98(1):41-50.

45: Choi JS, Bae WY, Park C, Jeong JW*. Zingerone activates VMAT2 during MPP(+) -induced Cell Death. Phytother Res. 2015 Nov;29(11):1783-90.

44: Kang HM, Sohn I, Kim S, Kim D, Jung J, Jeong JW, Park C. Optical measurement of mouse strain differences in cerebral blood flow using indocyanine green. J Cereb Blood Flow Metab. 2015 Jun;35(6):912-6.

43: Jang WJ, Jung SK, Kang JS, Jeong JW, Bae MK, Joo SH, Park GH, Kundu JK, Hong YS, Jeong CH. Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification. Cancer Sci. 2014 Oct;105(10):1245-53.

42: Kim W, Jeong JW, Kim JE. CCAR2 deficiency augments genotoxic stress-induced apoptosis in the presence of melatonin in non-small cell lung cancer cells. Tumour Biol. 2014 Nov;35(11):10919-29

41: Kong CS, Kim KH, Choi JS, Kim JE, Park C, Jeong JW*. Salicin, an extract from white willow bark, inhibits angiogenesis by blocking the ROS-ERK pathways. Phytother Res. 2014 Aug;28(8):1246-51.

40: Jin J, Kang HM, Jung J, Jeong JW, Park C. Related expressional change of HIF-1α to the neuroprotective activity of exendin-4 in transient global ischemia. Neuroreport. 2014 Jan 8;25(1):65-70.

39: Kang HM, Kang Y, Chun HJ, Jeong JW, Park C. Evaluation of the in vitro and in vivo angiogenic effects of exendin-4. Biochem Biophys Res Commun. 2013 Apr 26;434(1):150-4.

38: Nam YS, Cho SY, Yang HY, Park KS, Jang JH, Kim YT, Jeong JW, Suh JT, Lee HJ. Investigation of mutation distribution in DNA gyrase and topoisomerase IV genes in ciprofloxacin-non-susceptible Enterobacteriaceae isolated from blood cultures in a tertiary care university hospital in South Korea, 2005-2010. Int J Antimicrob Agents. 2013 Feb;41(2):126-9.

37: Kim EJ, Kim SY, Yun HJ, Kim CG, Jeong JW, Kim TH, Kim CH, Darroudi F, Kang CM. Detection and quantification of a radiation-associated mitochondrial DNA deletion by a nested real-time PCR in human peripheral lymphocytes. Mutat Res. 2012 Dec 12;749(1-2):53-9.

36: Kim KJ, Choi JS, Kang I, Kim KW, Jeong CH, Jeong JW*. Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model. J Pineal Res. 2013 Apr;54(3):264-70.

35: Kim KJ, Choi JS, Kim KW, Jeong JW*. The anti-angiogenic activities of glycyrrhizic acid in tumor progression. Phytother Res. 2013 Jun;27(6):841-6.

34: Kong CS, Jeong CH, Choi JS, Kim KJ, Jeong JW*. Antiangiogenic effects of p-coumaric acid in human endothelial cells. Phytother Res. 2013 Mar;27(3):317-23.

33: Kim SR, Jung YH, Park HJ, Kim MK, Jeong JW, Jang HO, Yun I, Bae SK, Bae MK. Upregulation of thromboxane synthase mediates visfatin-induced interleukin-8 expression and angiogenic activity in endothelial cells. Biochem Biophys Res Commun. 2012 Feb 24;418(4):662-8.

32: Kang YS, Bae MK, Kim JY, Jeong JW, Yun I, Jang HO, Bae SK. Visfatin induces neurite outgrowth in PC12 cells via ERK1/2 signaling pathway. Neurosci Lett. 2011 Oct 24;504(2):121-6.

31: Choi JS, Park SY, Yi EY, Kim YJ, Jeong JW*. Coenzyme Q10 decreases basic fibroblast growth factor (bFGF)-induced angiogenesis by blocking ERK activation. Oncol Res. 2011;19(10-11):455-61.

30: Park G, Jeong JW, Kim JE. SIRT1 deficiency attenuates MPP+-induced apoptosis in dopaminergic cells. FEBS Lett. 2011 Jan 3;585(1):219-24.

29: Kim SB, Lee D, Jeong JW, Kim C, Park D, Kim MG. Soluble epithin/PRSS14 secreted from cancer cells contains active angiogenic potential. Mol Cells. 2010 Jun;29(6):617-23.

28: Seo JH, Cha JH, Park JH, Jeong CH, Park ZY, Lee HS, Oh SH, Kang JH, Suh SW, Kim KH, Ha JY, Han SH, Kim SH, Lee JW, Park JA, Jeong JW, Lee KJ, Oh GT, Lee MN, Kwon SW, Lee SK, Chun KH, Lee SJ, Kim KW. Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation. Cancer Res. 2010 Jun 1;70(11):4422-32.

27: Park SY, Jang WJ, Yi EY, Jang JY, Jung Y, Jeong JW, Kim YJ. Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia. J Pineal Res. 2010 Mar;48(2):178-84.

26: Kim SY, Choi JS, Park C, Jeong JW. Ethyl pyruvate stabilizes hypoxia-inducible factor 1 alpha via stimulation of the TCA cycle. Cancer Lett. 2010 Sep 28;295(2):236-41.

25: Choi JS, Lee MS, Jeong JW*. Ethyl pyruvate has a neuroprotective effect through activation of extracellular signal-regulated kinase in Parkinson's disease model. Biochem Biophys Res Commun. 2010 Apr 9;394(3):854-8.

24: Choi JS, Park C, Jeong JW*. AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Biochem Biophys Res Commun. 2010 Jan 1;391(1):147-51.

23: Hwang DY, Hong S, Jeong JW, Choi S, Kim H, Kim J, Kim KS. Vesicular monoamine transporter 2 and dopamine transporter are molecular targets of Pitx3 in the ventral midbrain dopamine neurons. J Neurochem. 2009 Dec;111(5):1202-12.

22: Lee HJ, Ahn BJ, Shin MW, Jeong JW, Kim JH, Kim KW. Ninjurin1 mediates macrophage-induced programmed cell death during early ocular development. Cell Death and Differentiation. 2009; 16(10):1395-1407.

21: Ahn BJ, Lee HJ, Shin MW, Choi JH, Jeong JW, Kim KW. Ninjurin1 is expressed in myeloid cells and mediates endothelium adhesion in the brains of EAE rats. Biochem Biophys Res Commun. 2009 Sep 18;387(2):321-5.

20: Kim YS, Ahn KH, Kim SY, Jeong JW*. Okadaic acid promotes angiogenesis via activation of hypoxia-inducible factor-1. Cancer Lett. 2009 Apr 8;276(1):102-8

19: Ahn KH, Kim YS, Kim SY, Huh Y, Park C, Jeong JW*. Okadaic acid protects human neuroblastoma SH-SY5Y cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis. Neurosci Lett. 2009 Jan 9;449(2):93-7.

18: Jin J, Jing H, Choi G, Oh MS, Ryu JH, Jeong JW, Huh Y, Park C. Voluntary exercise increases the new cell formation in the hippocampus of ovariectomized mice. Neurosci Lett. 2008 Jul 18;439(3):260-3.

17: Oh SH, Woo JK, Jin Q, Kang HJ, Jeong JW, Kim KW, Hong WK, Lee HY. Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha. Int J Cancer. 2008 Jan 1;122(1):5-14.

16: Lee JW, Park JA, Kim SH, Seo JH, Lim KJ, Jeong JW, Jeong CH, Chun KH, Lee SK, Kwon YG, Kim KW. Protein kinase C-delta regulates the stability of hypoxia-inducible factor-1 alpha under hypoxia. Cancer Sci. 2007 Sep;98(9):1476-81.

15: Kim SH, Kim KW, Jeong JW*. Inhibition of hypoxia-induced angiogenesis by sodium butyrate, a histone deacetylase inhibitor, through hypoxia-inducible factor-1alpha suppression. Oncol Rep. 2007 Apr;17(4):793-7.

14: Kim SH, Jeong JW, Park JA, Lee JW, Seo JH, Jung BK, Bae MK, Kim KW. Regulation of the HIF-1alpha stability by histone deacetylases. Oncol Rep. 2007 Mar;17(3):647-51.

13: Moon HE, Cheon H, Chun KH, Lee SK, Kim YS, Jung BK, Park JA, Kim SH, Jeong JW, Lee MS. Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1alpha. Oncol Rep. 2006 Oct;16(4):929-35.

12: Bae MK, Kim SH, Jeong JW, Lee YM, Kim HS, Kim SR, Yun I, Bae SK, Kim KW. Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1. Oncol Rep. 2006 Jun;15(6):1557-62.

11: Kim SH, Park JA, Kim JH, Lee JW, Seo JH, Jung BK, Chun KH, Jeong JW, Bae MK, Kim KW. Characterization of ARD1 variants in mammalian cells. Biochem Biophys Res Commun. 2006 Feb 10;340(2):422-7.

10: Bae MK, Jeong JW, Kim SH, Kim SY, Kang HJ, Kim DM, Bae SK, Yun I, Trentin GA, Rozakis-Adcock M, Kim KW. Tid-1 interacts with the von Hippel-Lindau protein and modulates angiogenesis by destabilization of HIF-1alpha. Cancer Res. 2005 Apr 1;65(7):2520-5.

9: Bae SH, Jeong JW, Park JA, Kim SH, Bae MK, Choi SJ, Kim KW. Sumoylation increases HIF-1alpha stability and its transcriptional activity. Biochem Biophys Res Commun. 2004 Nov 5;324(1):394-400.

8: Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW. Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med. 2004 Feb 29;36(1):1-12.

7: Moon EJ, Jeong CH, Jeong JW, Kim KR, Yu DY, Murakami S, Kim CW, Kim KW. Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha. FASEB J. 2004 Feb;18(2):382-4.

6: Choi KS, Bae MK, Jeong JW, Moon HE, Kim KW. Hypoxia-induced angiogenesis during carcinogenesis. J Biochem Mol Biol. 2003 Jan 31;36(1):120-7.

5: Jeong JW, Bae MK, Ahn MY, Kim SH, Sohn TK, Bae MH, Yoo MA, Song EJ, Lee KJ, Kim KW. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell. 2002 Nov 27;111(5):709-20.

4: Bae MH, Jeong CH, Kim SH, Bae MK, Jeong JW, Ahn MY, Bae SK, Kim ND, Kim CW, Kim KR, Kim KW. Regulation of Egr-1 by association with the proteasome component C8. Biochim Biophys Acta. 2002 Oct 21;1592(2):163-7.

3: Bae MK, Ahn MY, Jeong JW, Bae MH, Lee YM, Bae SK, Park JW, Kim KR, Kim KW. Jab1 interacts directly with HIF-1alpha and regulates its stability. J Biol Chem. 2002 Jan 4;277(1):9-12

2: Jeong JW, Cha HJ, Yu DY, Seiki M, Kim KW. Induction of Membrane-Type Matrix Metalloproteinase-1 stimulates Angiogenic activities of the Bovine Aortic Endothelial Cells. Angiogenesis, 1999, 3 (2), 167-174.

1: Park MT, Cha HJ, Jeong JW, Kim SI, Chung HY, Kim ND, Kim OH, Kim KW. Glucocorticoid Receptor-induced Down-regulation of MMP-9 by Ginseng Components, PD and PT Contributes to Inhibition of the Invasive Capacity of HT1080 Human Fibrosarcoma Cells. Mol. Cells. 1999, 9(5), 476-483.

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