교수소개

연구전담 전임교원

연구전담 전임교원

연구전담 전임교원

김만석 교수

영문이름 -
Kim Man Seok
교실 -
연구전담 전임교원
전공 -
Electrical & Computer Engineering (Computational Systems Biology)
연락처 -
02-440-6242
연구실 -
강동경희대학교병원 신관(서희빌딩) 4층 질환모델중개연구소 I
E-mail -
manskim@khu.ac.kr
홈페이지 -
https://khuttrcenter.wordpress.com/home/cmol/
1. In-silico Metabolic Modeling (Metabolic Flux Simulation)
- Constraint-based Context Specific Metabolic Modeling

2. Multi-system-level Association Analysis
- Metabolome: Metabolic Simulation, Metabolism Enrichment Analysis
- Proteome: Protein-Protein-Interaction Network-based Probabilistic Inference
- Transcriptome: (Spatial Single-cell, Single-nuclei, Bulk) RNA-seq, ATAC-seq Analysis
- Genome: GTEx–GWAS–KOGES Association Analysis

3. Machine Learning (Deep Learning) based Analysis Approaches
1. BE, Mechanical Engineering, Sogang University, 2006
2. MS, Integrated Biotechnology, Sogang University, 2008
3. PhD, Electrical & Computer Engineering (Computational Systems Biology), Texas A&M University, 2016
4. Research Associate, Pathology & Microbiology, Texas A&M University, 2018
5. Research Fellow, Biomedical & Health Informatics, The Children’s Hospital of Philadelphia (University of Pennsylvania School of Medicine), 2021
6. Assistant Professor, Translational-Transdisciplinary Research Center, Clinical Research Institute, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University
1. NASA GeneLab AWG (Analysis Working Group) 한국 유일 멤버
2. COV-IRT (Covid-19 International Research Team) 한국 유일 멤버
3. Human Cell Atlas 네트워크
4. The Children’s Hospital of Philadelphia & University of Pennsylvania School of Medicine.
5. 경희대학교병원 (경희의료원, 강동경희대병원), 고대구로병원, 분당차병원, 서울대보라매병원, 세브란스 (신촌, 강남), 이대목동병원
- Aging and putative frailty biomarkers are altered by spaceflight
[Nature Communications, 2023]

- Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection
[Science Translational Medicine, 2023]

- Models of Cellular Metabolism from Single Cell Expression Data Reveals Cell Type Specific Metabolic Heterogeneity
[PLOS One, 2023]

- Transcriptome analysis of maize pathogen Fusarium verticillioides revealed FvLcp1, a secreted protein with type-D fungal LysM and Chitin-binding domains, that plays important roles in pathogenesis and mycotoxin production
[Microbiological Research, 2022]

Expression of AKT1 Related with Clinicopathological Parameters in Clear Cell Renal Cell Carcinoma
[Current Issues in Molecular Biology, 2022]

- Distinct function of mediator subunits in fungal development, stress response and secondary metabolism in fungal pathogen Fusarium verticillioides
[Phytopathology, 2022]

- Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact
[Cell, 2020]

- Scedar: a scalable Python package for single-cell RNA-seq exploratory data analysis
[PLOS Computational Biology, 2020]

- The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution
[Developmental Cell, 2019]

- Application of game theory to explore the dynamics of host-pathogen association in phytobiomes
[Phytobiomes Journal, 2018]

- Characterizing gene networks underpinning maize stalk rot virulence in Fusarium verticillioides through functional subnetwork module analyses
[Scientific Reports, 2018]

- Computational prediction of pathogenic network modules in Fusarium verticillioides
[IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018]

- Computational identification of genetic subnetwork modules associated with maize defense response to Fusarium verticillioides
[BMC Bioinformatics, 2015]

- Adaptive Reference Update (ARU) algorithm: A stochastic search algorithm for efficient optimization of multi-drug cocktails
[BMC Genomics, 2012]

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